Subungual keratoacanthoma
Subungual keratoacanthoma is a rare, rapidly growing tumor that occurs under the nail (subungual = beneath the nail). It’s a variant of keratoacanthoma, which is a generally benign but locally aggressive skin tumor that resembles squamous cell carcinoma.
They can be found under fingernails or toenails (usually thumb or big toe) and most common in middle-aged to older adults. They are painful, fast-growing, flesh-colored or reddish nodule under the nail. Symptoms include nail destruction, swelling, and sometimes bone involvement.
Treatment for Subungual keratoacanthoma
| Option | |
|---|---|
| Surgical excision | Mainstay of treatment. Complete removal is essential. |
| Mohs micrographic surgery | Considered when malignancy cannot be ruled out. |
| Amputation (rare) | May be considered if bone is involved or lesion is aggressive. |
| Follow-up | Needed to monitor for recurrence or malignancy |
Why It’s Important
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It mimics cancer (SCC), so misdiagnosis is possible.
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It can destroy the nail and even underlying bone if left untreated.
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It’s rare, so awareness among clinicians and patients is important to avoid delayed diagnosis.
If you’re a patient, it’s crucial to consult a podiatrist or dermatologist or specialist in skin tumors for an accurate diagnosis and treatment plan.
We are independent prescribers able to prescribe any medication from the BNF relevant to the lower limb, foot and ankle.
Are you suffering from any hand or foot condition? At The Chelsea Clinic, we can help. One of our podiatrists can assist and then recommend what treatments are best to get you back on track. Podiatrist South Kensington
Schedule an appointment here or you may call us at +44 (0) 207 101 4000.
We hope you have a feetastic day!
-The Chelsea Clinic and Team
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Learn more about our blog Five Steps for Effective Foot Care
